Complete genome analysis of , a species inhibiting O157:H7.

Introduction: Bacteriophages infecting human pathogens have been considered potential biocontrol agents, and studying their genetic content is essential to their safe use in the food industry. is a bacteriophage named UFV-AREG1, isolated from cowshed wastewater and previously tested for its ability to inhibit O157:H7.

Methods: 1 was previously isolated using E.

Genomic Characterisation of UFJF_PfDIW6: A Novel Lytic -Phage with Potential for Biocontrol in the Dairy Industry.

In this study, we have presented the genomic characterisation of UFJF_PfDIW6, a novel lytic -phage with potential for biocontrol in the dairy industry. This phage showed a short linear double-stranded DNA genome (~42 kb) with a GC content of 58.3% and more than 50% of the genes encoding proteins with unknown functions.

Encapsulation in alginate-polymers improves stability and allows controlled release of the UFV-AREG1 bacteriophage.

The bacteriophage UFV-AREG1 was used as a model organism to evaluate the encapsulation via extrusion using different hydrocolloids. Pure alginate [0.75%, 1.

Bacteriophages that infect Gram-negative bacteria as source of signal-arrest-release motif lysins.

Treatment of infections caused by multidrug-resistant (MDR) Gram-negative bacteria is challenging, a potential solution for which is the use of bacteriophage-derived lytic enzymes. However, the exogenous action of bacteriophage lysins against Gram-negative bacteria is hindered due to the presence of an impermeable outer membrane in these bacteria. Nevertheless, recent research has demonstrated that some lysins are capable of permeating the outer membrane of Gram-negative bacteria with the help of signal peptides.