Behavioral changes with paranoia in an elderly woman taking atorvastatin.

Background: There have been a number of published reports of central nervous system (CNS) adverse effects with statins.

Case Summary: A 79-year-old woman developed paranoia, anxiety, and behavioral changes approximately 2.5 weeks after starting atorvastatin 10 mg/d.

Hypothesized predictors of patient-physician trust and distrust in the elderly: implications for health and disease management.

This study notes the differences between trust and distrust perceptions by the elderly as compared with younger populations. Given the importance of trust and distrust in compliance, changing behaviors, and forming partnerships for both health and disease management, it is necessary to be able to measure patient-doctor trust and distrust (PDTD). Following recent conceptualizations on trust and distrust as coexistent states, this study hypothesizes predictors of PDTD.