Publications by authors named "Maryanna Martina Perrotta"

In recent years, plastic pollution has become a growing environmental concern: more than 350 million tons of plastic material are produced annually. Although many efforts have been made to recycle waste, a significant proportion of these plastics contaminate and accumulate in the environment. A central point in plastic pollution is demonstrated by the evidence that plastic objects gradually and continuously split up into smaller pieces, thus producing subtle and invisible pollution caused by microplastics (MP) and nanoplastics (NP).

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In the model system for genetics, , sexual differentiation and male courtship behavior are controlled by sex-specific splicing of () and (). In vitro and in vivo studies showed that female-specific Transformer (TRA) and the non-sex-specific Transformer 2 (TRA2) splicing factors interact, forming a complex promoting and female-specific splicing. TRA/TRA2 complex binds to 13 nt long sequence repeats in their pre-mRNAs.

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In the last decades, the colonization of Mediterranean Europe and of other temperate regions by Aedes albopictus created an unprecedented nuisance problem in highly infested areas and new public health threats due to the vector competence of the species. The Sterile Insect Technique (SIT) and the Incompatible Insect Technique (IIT) are insecticide-free mosquito-control methods, relying on mass release of irradiated/manipulated males, able to complement existing and only partially effective control tools. The validation of these approaches in the field requires appropriate experimental settings, possibly isolated to avoid mosquito immigration from other infested areas, and preliminary ecological and entomological data.

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In insects, rapidly evolving primary sex-determining signals are transduced by a conserved regulatory module controlling sexual differentiation. In the agricultural pest (Mediterranean fruit fly, or Medfly), we identified a Y-linked gene, (), encoding a small protein that is necessary and sufficient for male development. Silencing or disruption of in XY embryos causes feminization, whereas overexpression of in XX embryos induces masculinization.

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