Publications by authors named "Maryamalsadat Mousavi"
Role of Donors and Recipients' Glutathione S-Transferase Gene Polymorphisms in Association of Oxidative Stress With Delayed Graft Function in Kidney Allograft Recipients.
Jalal Azmandian Ali Mandegary Mahboobeh Pootari Mohamad-Hadi Nematolahi Mohammad-Reza Ebadzadeh Maryamalsadat Mousavi
Iran J Kidney Dis
May 2017
Article Synopsis
- Oxidative stress plays a key role in delayed graft function (DGF) following kidney transplantation, and glutathione S-transferases (GSTs) are genes that produce enzymes that help combat this stress.
- A study of 182 donor-recipient pairs found that higher lipid peroxidation levels correlated with DGF, and recipients with the GSTM1 null variant had a greater risk of DGF.
- The findings indicate that both donor and recipient GSTM1 polymorphisms are significant risk factors for oxidative stress, which negatively impacts kidney transplant outcomes.