Publications by authors named "Maryam Zarin"

Pyroptosis can be triggered through both canonical and non-canonical inflammasome pathways, involving the cleavage of gasdermin (GSDM) protein family members, like GSDMD and GSDME. The impact of pyroptosis on tumors is nuanced, because its role in regulating cancer progression and anti-tumor immunity may vary depending on the tumor type, stage, location, and immune status. However, pyroptosis cannot be simply categorized as promoting or inhibiting tumors based solely on whether it is acute or chronic in nature.

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Article Synopsis
  • * MicroRNAs (miRNAs) are small RNA molecules that play a key role in regulating inflammation by interacting with the 3'-untranslated regions (3'-UTR) of inflammatory genes.
  • * This paper examines the impact of single nucleotide polymorphisms (SNPs) in miRNA binding sites within inflammatory genes and identifies 110 promising miRSNPs in 176 inflammatory genes that could be potential targets for future CRC research.
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Sideroblastic anemias are heterogeneous rare hematological disorders, representing diverse phenotypes. In this study, the genetic cause of congenital, transfusion dependent anemia in four unrelated families consisting of eighteen individuals, with one affected member was investigated. Probands were suspected to rare anemias, including sideroblastic anemia.

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