Rapid Analysis of Acrylamide in Tap and Well Water Samples by Solvent Terminated Dispersive Liquid-Liquid Microextraction Followed by GC-FID.

A fast, green and low cost method for analysis of acrylamide in tap and well water has been presented for the first time using solvent terminated-dispersive liquid liquid microextraction (ST-DLLME) with a simple equipment which does not need centrifugation step followed by GC-FID. The use of one variable at a time optimization method revealed that methanol and octanone were the superior disperser and extraction solvents, respectively. A central composite design (CCD) as a response surface methodology was used for multivariate optimization of five independent factors (volumes of extraction and dispersive solvents, pH, salt addition and extraction time) on the extraction efficiency.

Light Reflectance Spectroscopy to Detect Positive Surgical Margins on Prostate Cancer Specimens.

Purpose: Intraoperative frozen section analysis is not routinely performed to determine positive surgical margins at radical prostatectomy due to time requirements and unproven clinical usefulness. Light reflectance spectroscopy, which measures light intensity reflected or backscattered from tissues, can be applied to differentiate malignant from benign tissue. We used a novel light reflectance spectroscopy probe to evaluate positive surgical margins on ex vivo radical prostatectomy specimens and correlate its findings with pathological examination.

Epithelioid hemangioendothelioma in pleural effusion.

Epithelioid hemangioendothelioma (EHE) is a rare mesenchymal tumor of vascular origin with variable morphological features and unpredictable biological behavior. EHE occasionally involves the pleural fluid. However, the cytomorphology of EHE found in pleural fluid has not been well characterized in the literature.