Comparing sucrose solution with distilled water for pain management in premature infant venipuncture: randomized clinical trial.

Introduction And Importance: Managing pain is critical, especially for premature infants undergoing frequent painful procedures. Uncontrolled pain can lead to lasting harm in growth, cognitive development, and future pain responses.

Methods: A double-blinded clinical investigation involving 150 premature infants was performed in a neonatal intensive care unit.