Publications by authors named "Maryam Saadat"

Article Synopsis
  • The study aimed to evaluate the effectiveness of adding cervical spine manual therapy (CMT) to conventional physical therapy (PT) for improving outcomes in patients with carpal tunnel syndrome (CTS).
  • Forty-eight patients were split into two groups: one received PT alone, while the other received PT plus CMT, with various assessments conducted at baseline, after treatment, and six months later.
  • Results indicated that the CMT group experienced significantly better improvements in pain levels and nerve function compared to the PT-only group, suggesting that combining CMT with PT could be a more effective treatment for CTS.
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  • A study was conducted to compare the effectiveness of the Autar and Padua risk assessment scales in predicting venous thromboembolism (VTE) among 228 ICU patients.
  • Results showed the Autar scale had a higher predictive accuracy (AUC of 0.61) compared to the Padua scale (AUC of 0.53), although both scales demonstrated high sensitivity (100%) but low specificity.
  • The findings suggest that the Autar scale is more reliable for assessing VTE risk in ICU patients and is recommended for guiding prophylactic treatment.
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Background And Objective: This study aimed to compare physical and cognitive functions between post-coronavirus disease 2019 (COVID-19) participants and healthy matched controls and investigate associations between physical and cognitive impairments with quality of life.

Methods: Twenty-three post-COVID-19 participants and 23 age and sex-matched healthy people without a history of COVID-19 were included. Physical function was assessed using the Medical Research Council Sum Score (MRC-SS), 2 min Step Test, Modified Borg Scale, and Short Physical Performance Battery (SPPB) Test.

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Thymoquinone (THQ) and its nanoformulation (NFs) have emerged as promising candidates for the treatment of neurological diseases due to their diverse pharmacological properties, which include anti-inflammatory, antioxidant, and neuroprotective effects. In this study, we conducted an extensive search across reputable scientific websites such as PubMed, ScienceDirect, Scopus, and Google Scholar to gather relevant information. The antioxidant and anti-inflammatory properties of THQ have been observed to enhance the survival of neurons in affected areas of the brain, leading to significant improvements in behavioral and motor dysfunctions.

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  • Prenatal exposure to valproic acid (VPA) in rats increases the risk of autism-like behaviors in their offspring, which the study aimed to investigate using Prangos ferulacea as a potential treatment.!
  • Pregnant rats were given VPA or saline, and their pups received varying doses of Prangos ferulacea after birth, with behavioral tests conducted to evaluate the pups' responses at different ages.!
  • Results showed that Prangos ferulacea effectively reversed behavior changes and oxidative stress caused by VPA, suggesting its potential as a treatment to mitigate autism spectrum disorder symptoms. !
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Introduction: Fear avoidance beliefs questionnaire (FABQ), Tampa scale of kinesiophobia (TSK), and pain catastrophizing scale (PCS) are tools widely used to measure fear-avoidance beliefs, fear of movement, and pain-related catastrophic thinking in people with chronic spinal disorders.

Purpose: To evaluate responsiveness and minimal important change (MIC) for the Persian version of FABQ, TSK, and PCS.

Method: One hundred people with chronic non-specific neck pain participated in an intervention program including routine physiotherapy plus pain neuroscience education.

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Background: Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy that has a significant impact on patients' quality of life. Current physical therapy treatment options show limited effects or low-quality evidence, especially in the long term. To date, there has been little research to look at the effects of treating the cervical spine on decreasing symptoms distally to the carpal tunnel.

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Background And Purpose: Chronic neck pain has a significant impact on the patient's quality of life. Specific outcome measures like Copenhagen Neck Functional Disability Index (CNFDI), Neck Bournemouth questionnaire (NBQ), and Spine Functional Index (SFI) are reliable and valid measures that have been used for comprehensively evaluating neck-related disabilities. However, responsiveness has not yet been investigated.

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Background: The Functional Arm Scale for Throwers (FAST) is a reliable and valid region-specific tool designed to evaluate health-related quality of life in throwing athletes with upper-extremity injuries. The purpose of this study was to adapt, translate, and evaluate the psychometric properties of the Persian version of the Functional Arm Scale (FAST-Persian) for use in throwing athletes.

Materials And Methods: The study was conducted based on 5 steps of cross-cultural adaptation including forward translation, synthesis, backward translation, expert committee review, and pretesting.

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  • - This study investigated the effects of Japanese sake yeast on Alzheimer-type dementia in rats, focusing on behavioral and biochemical changes associated with the condition.
  • - Results indicated that Alzheimer rats exhibited increased anxiety, depression, and inflammatory markers, along with decreased brain-derived neurotrophic factor (BDNF) levels.
  • - Administration of sake at higher doses significantly reduced anxiety and depression behaviors and improved BDNF levels, suggesting potential neuroprotective effects that warrant further investigation into its mechanisms.
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Objective: The aim of this study was to evaluate and compare the effects of chlorhexidine, quercetin, and α-tocopherol on the shear bond strength of universal adhesives in the short (24h) and long term (6 months).

Material And Methods: Ninety-six extracted sound molars were collected and divided randomly into four groups: control (no treatment), 2% chlorhexidine, 10% α-tocopherol, and 1% quercetin. The solutions were prepared and applied to the teeth for 60 s, followed by application of All-Bond universal adhesive and composite build-up.

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Objective: This study aimed to evaluate and compare the impacts of the postbleaching application of sodium ascorbate, alpha-tocopherol, and quercetin on the shear bond strength (SBS) of composite resin.

Material And Methods: 60 extracted intact maxillary first premolars were collected and were randomly divided into five experimental groups as follows (n=12): Group A (negative control): no bleaching, Group B (positive control): bleaching with 40% hydrogen peroxide (HP), Group C: HP±10% sodium ascorbate for 10min, Group D: HP±10% alpha-tocopherol for 10min, and Group E: HP±1% quercetin for 10min. Composite bonding was done immediately after bleaching for Groups B-E and without any treatment for Group A.

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The aim of this study is to investigate the effects of combining routine physical therapy with pain neuroscience education (PNE) on psychosocial factors, physical performance, and the experienced pain in patients with chronic neck pain (CNP). This study is a double-blind randomized clinical trial in which patients will be randomly allocated to two groups, routine physical therapy with and without PNE. Patients will be assessed at the baseline, post intervention, and three months later.

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The purpose of this study was to evaluate the performance of a resin-modified glass ionomer cement (RMGIC) to which bacterial cellulose nanocrystals (BCNs) were added. BCNs were incorporated into the RMGIC powder in ratios of 0.3%, 0.

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Introduction: Lipid-based nano-drug delivery systems (LBNDDSs) have gained widespread attention in oral drug delivery due to their tunable and versatile properties such as biocompatibility and biodegradability, which makes them promising delivery systems for a variety of therapeutics. Currently, different types of LBNDDSs including liposomes, micelles, nanoemulsions, and solid lipid nanoparticles (SLNs) are developed for drug delivery applications. SLNs can be used as a controlled drug delivery system for oral delivery applications.

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Background: The present study aimed to investigate the effect of bacterial cellulose nanocrystals (BCNC) on the shear bond strength (SBS) of resin modified glass ionomer cement (RMGIC) to dentin.

Material And Methods: A total of 48 freshly extracted intact third molars were randomly divided into four main groups with three different concentrations (0.3%, 0.

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Background: Several studies have investigated cervical kinematic performance in patients with chronic neck pain, especially with fast movements. A recent systematic review recommended further study of cervical spine kinematics cervical motions in individuals with neck pain.

Objectives: This study aimed to examine cervical spine kinematics of naturally paced cervical motions in patients with chronic neck pain compared with a group of asymptomatic participants.

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Objectives:  The purpose of this study was to evaluate the effect of bacterial cellulose nanocrystals (BCNCs) on the mechanical properties of resin-modified glass ionomer cements (RMGICs) including compressive strength (CS), diametral tensile strength (DTS), and modulus of elasticity ().

Materials And Methods:  BCNCs were incorporated into RMGIC at various concentrations (0.3, 0.

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Objective: This study examined the effects of combining traditional physical therapy exercises with sensorimotor training on joint position sense, pain, muscle endurance, balance and disability in patients with chronic, non-specific neck pain.

Design: Double-blind, randomized controlled trial.

Subjects: A total of 53 patients with chronic non-specific neck pain were randomized to either traditional or combined exercise groups.

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Background: Clinicians and researchers commonly use responsive outcome measures to interpret changes in a patient's condition as a result of an intervention. This study was conducted to assess the ability of the Persian version of Neck Disability Index and Functional Rating Index to detect responsiveness in the patients with neck pain.

Methods: A diagnostic accuracy study was done in Ahvaz, Iran, 2016.

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Article Synopsis
  • Cardiac rehabilitation (CR) improves patient outcomes after heart attacks, but participation rates are low; the study develops a web-based telerehabilitation platform to boost engagement in self-management for post-myocardial infarction patients.!
  • The development process of the platform involved four phases: need assessment, prototype design, implementation, and usability evaluation, resulting in an Android app and web dashboard for both patients and mentors.!
  • The platform includes features like self-assessments, educational content, and communication tools, achieving a mean usability score indicating acceptable levels for patients (75.16) and clinicians (73.33), demonstrating its effectiveness for those unable to attend in-person rehabilitation.!
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Liposome as a revolutionizing carrier, has exhibited favorable aspects in drug delivery. However, there are numerous challenges affecting its effectiveness. Hypersensitivity, accelerated blood clearance, opsonization, uptake by reticulo-endothelial system, and also immune suppression are known as the dominant manifestations of immune-related effects.

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The aim of this review was to describe the preferred charged nano-particles (CNPs) for targeted delivery in tumor cells. Zeta Potential (ZP), which represents the surface charge of NPs was highlighted in cell entrance and interactions. In this regard, various types of endocytosis pathways which are involved in NPs' uptake were first introduced.

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Impairment of cervical sensory input in patients with neck pain may disturb postural stability. The purpose of present study was to assess the dynamic postural stability of subjects with chronic neck pain compared to a matched control group. In this case-control study, 22 chronic non-specific neck pain and 22 healthy individuals participated.

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Background: This study evaluated the effect of three different silanes and post-silanization treatments on the retentive strength of fiber posts luted with an etch-and-rinse resin cement.

Material And Methods: One hundred intact maxillary central incisors were randomly divided into 10 groups after endodontic treatment and post space preparation (n=10). The fiber posts were etched using 24% hydrogen peroxide.

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