The Effect of Fingolimod on Renal Ischemia/Reperfusion Injury in a Rat Model.

Background: Ischemia/reperfusion injury (IRI) is a leading cause of acute kidney injury (AKI) that induces inflammation and oxidative stress. The main goal of the current study was to assess the impact of fingolimod on kidney IRI in rats.

Methods: For this purpose, 18 male Wistar rats (220-250g) were divided into three groups including (i) Sham, (ii) I/R, and (iii) fingolimod+I/R.

Solid-state photochromism of spironaphthoxazine loaded microcapsules with photo-patterning and thermo-regulating features.

Hypothesis: One of the biggest challenges in the field of photoresponsive spirooxazines is their fast reverse isomerization. Polar phase change materials beside spirooxazines not only stabilize their colored-form, but also induce thermo-regulating properties to the whole system. Moreover, encapsulation is a key route to protect them and provide safe application of photochromic materials in solid-state matrices.

High performance cyanide sensing with tunable limit of detection by stimuli-responsive gold nanoparticles modified with poly (N,N-dimethylaminoethyl methacrylate).

Detection of cyanide ion (CN) and design of new sensors with high sensitivity and selectivity are interesting topics in recent developments. Cyanide ions lead to immediate dissolution of gold nanoparticles (AuNPs) and distinct color changes from red to transparent colorless solution. The presence of any material e.