Gastroenterol Hepatol Bed Bench
January 2020
Aim: The current study aimed to identify the expression levels of (), , () in gastric cancer tissues and their corresponding adjacent non-cancerous tissues (ANCTs).
Background: SET has been first identified as a component of a fusion protein produced by chromosomal rearrangement in a patient with acute undifferentiated leukemia. Subsequently, multiple functions have been attributed to this gene in different disorders such as cancer and Alzheimer's disease.
Aim: To evaluate the expression of the growth arrest-specific 8 (GAS8) and its antisense (GAS8-AS1) in gastric cancer.
Background: GAS8 exists in a genomic region that is recurrently deleted in breast and prostate cancer. This gene contains a long non-coding RNA, namely GAS8-AS1 whose roles in the regulation of GAS8 has been reported in hepatocytes.