Impact of Alignments on the Accuracy of Protein Subcellular Localization Predictions.

Alignments in bioinformatics refer to the arrangement of sequences to identify regions of similarity that can indicate functional, structural, or evolutionary relationships. They are crucial for bioinformaticians as they enable accurate predictions and analyses in various applications, including protein subcellular localization. The predictive model used in this article is based on a deep - convolutional architecture.

SCLpred-ECL: Subcellular Localization Prediction by Deep N-to-1 Convolutional Neural Networks.

The subcellular location of a protein provides valuable insights to bioinformaticians in terms of drug designs and discovery, genomics, and various other aspects of medical research. Experimental methods for protein subcellular localization determination are time-consuming and expensive, whereas computational methods, if accurate, would represent a much more efficient alternative. This article introduces an ab initio protein subcellular localization predictor based on an ensemble of Deep N-to-1 Convolutional Neural Networks.

Protein subcellular localization prediction tools.

Protein subcellular localization prediction is of great significance in bioinformatics and biological research. Most of the proteins do not have experimentally determined localization information, computational prediction methods and tools have been acting as an active research area for more than two decades now. Knowledge of the subcellular location of a protein provides valuable information about its functionalities, the functioning of the cell, and other possible interactions with proteins.