Evaluation of Rosuvastatin Therapy on Gene Expression in Patients with Multiple Sclerosis: An Uncontrolled Clinical Trial.

Background: Multiple sclerosis (MS) is a chronic autoimmune disease. Current medications have some limitations such as low efficacy and high side effects. In recent years, statins have been raised as potential therapeutics for MS treatment with minimal complications.

Effects of L-carnitine supplementation in patients with mild-to-moderate COVID-19 disease: a pilot study.

Background: The present single-center clinical trial was designed to evaluate the potential benefits of L-carnitine supplementation in patients with COVID-19 disease.

Methods And Patients: The study was conducted on 75 patients with mild-to-moderate COVID-19 hospitalized in Shahid Beheshti Hospital-Hamadan, IRAN. The participants were randomly divided into intervention (n = 32) and control groups (n = 43).

Effects of vitamin D supplementation on the bone specific biomarkers in HIV infected individuals under treatment with efavirenz.

Background: It was reported that antiretroviral drugs such as efavirenz can increase the catabolism of vitamin D in HIV infected individuals. We have not found any study that evaluated effects of vitamin D supplementation on the bone specific biomarkers in HIV positive patients under treatment with antiretroviral regimen containing efavirenz.

Findings: Vitamin D deficiency was detected in 88.

Serum vitamin D concentration and potential risk factors for its deficiency in HIV positive individuals.

Human immunodeficiency virus (HIV) infected individuals are prone to malnutrition, and deficiencies of some minerals and vitamins. The aim of this study is to evaluate the frequency of vitamin D deficiency and determine the possible risk factors associated with this problem in HIV-infected individuals. This cross-sectional study was performed on 98 adult patients referred to the Emam Khomeini Hospital Complex, Tehran, Iran.