Publications by authors named "Maryam Azadmanesh"
Curr Mol Med
September 2024
Article Synopsis
- Oxidative stress occurs when there's an imbalance between harmful reactive species and the body's ability to eliminate them, playing a role in various disorders, including epilepsy, which is marked by unpredictable seizures.
- The protein Nrf2, known for its role in regulating the response to oxidative stress, activates detoxifying genes when it escapes the Keap1 protein and moves to the nucleus.
- Research suggests that activating Nrf2 through certain compounds, such as Berberis alkaloids and pentoxifylline, shows promise in treating epilepsy by mitigating oxidative stress.
