Caveolin-1 expression in odontogenic cysts and ameloblastomas.

Objective: The aim of this study is to evaluate the caveolin-1 expression in a group of odontogenic cysts and tumors.

Material And Method: In this cross-sectional study, the expression of caveolin-1 was evaluated immunohistochemically in 75 samples including 18 cases of dentigerous cyst, 18 odontogenic keratocysts, 3 orthokeratinized odontogenic cysts, 2 calcifying odontogenic cysts and 34 ameloblastomas (solid and unicystic).

Results: Positive immunohistochemical reaction was found in 100% of odontogenic cysts and this was significantly more than both unicystic (65%) and solid (55%) ameloblastomas.

Serum levels of osteopontin as a prognostic factor in patients with oral squamous cell carcinoma.

Osteopontin (OPN) is a multifunctional glycophosphoprotein that was detected in many carcinomas, and it may have a prognostic role. The aim of this study was to determine osteopontin serum levels in patients with oral squamous cell carcinoma (OSCC) and investigated its correlation with clinicopathological features of tumor. Using an ELISA kit, we assessed and compared the circulating levels of OPN in blood serum of 45 oral squamous cell carcinoma patients with 45 healthy control samples.

Rapidly growing lesions involving the maxilla in infants: a two-case presentation and deferential diagnosis.

Several pathologic lesions can be responsible for rapid swelling of the maxilla during infancy. Two of these uncommon lesions are melanotic neuroectodermal tumor of infancy (MNTI) and myofibroma. Despite these lesions being benign, they can have a destructive behavior that needs a meticulous diagnosis and early intervention.