Publications by authors named "Mary-France Courcoux"

Article Synopsis
  • A nationwide study in France investigated factors influencing treatment initiation versus watchful waiting in children with primary immune thrombocytopenia (ITP) and predicted chronic cases after 12 months.
  • The study included 257 children aged 6 months to 18 years, revealing that over 80% began treatment, primarily due to low platelet counts and bleeding symptoms.
  • Key predictors of chronicity included being female, older age (10 years or older), and higher platelet counts, while younger children demonstrated a better prognosis overall.
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The paediatric haematology day hospital administers almost all types of chemotherapy used to treat acute lymphoblastic leukaemia. Blood transfusions, myelograms and lumbar punctures are also performed there. The prevention of pain and anxiety generated by the care is a priority.

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A minority of children with chronic immune thrombocytopenia (ITP) require therapeutic intervention to prevent haemorrhagic risk. This retrospective national study evaluated romiplostim in childhood non-responsive or refractory chronic ITP. Between 2009 and 2012, 10 patients whose Buchanan score was 3-4 were treated with romiplostim.

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