Am J Ophthalmol Case Rep
March 2023
Epilepsy is a complex neurological condition characterized by repeated spontaneous seizures and can be induced by initiating seizures known as status epilepticus (SE). Elaborating the critical molecular mechanisms following SE are central to understanding the establishment of chronic seizures. Here, we identify a transient program of molecular and metabolic signaling in the early epileptogenic period, centered on day five following SE in the pre-clinical kainate or pilocarpine models of temporal lobe epilepsy.
View Article and Find Full Text PDFPurpose: Longitudinally visualizing relative blood flow speeds within choroidal neovascularization (CNV) may provide valuable information regarding the evolution of CNV and the response to vascular endothelial growth factor (VEGF) inhibitors.
Design: Retrospective, longitudinal case series conducted at the New England Eye Center.
Participants: Patients with either treatment-naïve or previously treated CNV secondary to neovascular age-related macular degeneration.