Publications by authors named "Mary Spence"
J Autism Dev Disord
July 2024
Article Synopsis
- CDKL5 deficiency disorder (CDD) causes early-onset epilepsy along with lifelong cognitive and motor challenges, highlighting the need for effective communication assessment tools.
- The study assessed the Communication and Symbolic Behavior Scales-Developmental Profile Infant Toddler Checklist (CSBS-DP ITC) with 150 caregivers, revealing a "floor effect," where many participants scored low, limiting the tool's effectiveness.
- While test-retest reliability was excellent, the poor performance on the three-factor model suggests that the CSBS-DP ITC may not be sensitive enough to track changes in communication for clinical trials involving CDD.
