Indolent systemic mastocytosis (ISM) is the most common form of systemic mastocytosis, and its diagnostic challenges and impact on patients' lives need more examination.
A survey of 40 adults with ISM revealed a lengthy diagnosis process, averaging over two years, with many patients experiencing severe symptoms that negatively affected their quality of life and work ability.
The study found a strong correlation between symptom severity and physical/mental health scores, highlighting that those with moderate to severe symptoms suffered significantly more from skin and gastrointestinal issues compared to those with mild symptoms.