Effects of a pre-workout supplement on hyperemia following leg extension resistance exercise to failure with different resistance loads.

Background: We sought to determine if a pre-workout supplement (PWS), containing multiple ingredients thought to enhance blood flow, increases hyperemia associated with resistance training compared to placebo (PBO). Given the potential interaction with training loads/time-under-tension, we evaluated the hyperemic response at two different loads to failure.

Methods: Thirty males participated in this double-blinded study.