Publications by authors named "Mary Mc Loughlin"

Objective: To determine the effect of the administration of oral gabapentin (20 mg/kg) and trazodone (8 mg/kg) on the MAC of isoflurane in dogs.

Methods: 6 adult dogs (3 castrated males and 3 spayed females), aged 13.3 ± 1.

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Objective: To evaluate the role of simulation models and previous surgical experience on subjective and objective stress levels of students performing their 1st elective surgery within the veterinary curriculum.

Sample: 141 third-year veterinary students.

Methods: Using a pre-post experimental design, salivary alpha-amylase, and cortisol were evaluated as markers of physiologic stress response before students' first elective surgery.

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Objective: Compare veterinary student success at urethral catheterization of small female cats and dogs using traditional and novel 2-catheter techniques.

Animal: Healthy anesthetized female cats ( = 23) and dogs ( = 6) weighing < 10 kg undergoing elective ovariohysterectomy.

Procedure: Two junior (Year 3) veterinary students with no previous urethral catheterization experience participated.

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Case Series Summary: Ear canal neoplasia is uncommon in cats. Ceruminous gland adenocarcinoma is the most frequently reported malignant neoplasm of the feline ear canal, and squamous cell carcinoma (SCC) is the most common malignant neoplasm diagnosed in the feline middle ear. However, limited information exists on the outcome of cats diagnosed with SCC of the ear canal, middle or inner ear.

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Objectives: To describe a novel technique for partial anatomic penile amputation using a thoracoabdominal stapler in dogs and to report any associated short-term peri-operative complications and clinical outcomes associated with the procedure.

Materials And Methods: Medical records from a tertiary referral hospital were reviewed for dogs undergoing penile amputation and scrotal urethrostomy between October 2007 and December 2019. Data collected included patient signalment, clinical signs on presentation, indication for penile amputation, surgical technique, duration of surgery, post-operative complications, and short-term outcome.

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Objective: To determine whether previous corrective upper airway surgery in brachycephalic dogs would decrease perianesthetic complications in subsequent anesthetic events.

Animals: 45 client-owned dogs.

Procedures: Brachycephalic dogs undergoing any combination of staphylectomy, nasal alaplasty, or laryngeal sacculectomy that were anesthetized at a later date for additional surgical procedures or imaging from August 2, 2007, to February 8, 2019, had their medical records reviewed during both anesthetic events for signalment, American Society of Anesthesiologists status, perianesthetic drug administration, anesthetic duration, presence and total time of positive-pressure ventilation, procedure invasiveness, and perianesthetic complications such as bradycardia, hypothermia, hypotension, cardiac arrhythmias, hypertension, vomiting or regurgitation, dysphoria, respiratory distress, hypoxemia, reintubation, and prolonged periods of recovery.

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Objective: To evaluate a novel 2-catheter technique for urethral catheterization in female cats and small dogs and compare the time required for and success rates achieved by use of the novel technique versus traditional methods (blind technique in cats and digital palpation in dogs) as performed by personnel (catheter placers [CPs]) with different levels of experience in urinary catheter placement.

Animals: 39 healthy sexually intact female animals (24 cats and 15 dogs weighing < 10 kg).

Procedures: 2 CPs were board certified in veterinary surgery, 1 of whom had experience with the novel technique, and the other did not.

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Objective: To determine the effect of oral administration of gabapentin (20 mg/kg) on the minimum alveolar concentration (MAC) of isoflurane in dogs.

Animals: 6 healthy adult dogs (3 males and 3 females with a mean ± SD body weight of 24.8 ± 1.

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Objective: To determine the effect of oral trazodone on the minimum alveolar concentration (MAC) of isoflurane in dogs.

Study Design: Prospective blinded, single-observer, randomized crossover experimental study.

Animals: Six adult (age 6.

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OBJECTIVE To determine whether brachycephalic dogs were at greater risk of anesthesia-related complications than nonbrachycephalic dogs and identify other risk factors for such complications. DESIGN Retrospective cohort study. ANIMALS 223 client-owned brachycephalic dogs undergoing general anesthesia for routine surgery or diagnostic imaging during 2012 and 223 nonbrachycephalic client-owned dogs matched by surgical procedure and other characteristics.

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Objective: To report the successful management of a dog with septic peritonitis and septic shock secondary to enterectomy dehiscence using novel techniques for identification of intestinal dehiscence and for septic shock treatment.

Case Summary: A 5-year-old castrated male Bernese Mountain Dog presented for lethargy 6 days following enterotomy for foreign body obstruction. Septic peritonitis was identified due to dehiscence of the enterotomy site, and resection and anastomosis were performed using a gastrointestinal anastomosis and thoracoabdominal stapling device.

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Objective: To describe a laparoscopic approach for placement of a percutaneously controlled artificial urethral sphincter (AUS) in female cadaver dogs and compare the change in urethral pressure and lumen diameter after filling the device.

Study Design: Experimental study.

Animals: Canine female cadavers (n = 10).

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Urinary incontinence in juvenile female dogs is often associated with urogenital anatomic anomalies. Study objectives include: (1) determine hospital prevalence of urinary incontinence in juvenile female soft-coated wheaten terriers (SCWTs) compared to other affected dogs; (2) characterize anatomic anomalies affecting urinary incontinent juvenile female SCWTs utilizing uroendoscopy; and (3) compare incidence of ectopic ureters, paramesonephric remnants, and short urethras in juvenile female urinary incontinent SCWTs to other juvenile female dogs with urinary incontinence. We hypothesize juvenile SCWTs have an increased prevalence of urinary incontinence and an increased incidence of ectopic ureters, paramesonephric remnants, and short urethras compared to non-SCWTs with urinary incontinence within our hospital population.

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Objective: To describe a suture-free ureterovesical anastomosis using a microvascular anastomotic system (MAS) and compare the surgical time and bursting pressure to a sutured ureterovesical anastomosis (SA) with and without an extravesical seromuscular tunnel (EVSMT).

Study Design: Randomized, unblocked design, ex vivo study.

Animals: Three canine cadavers.

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Objective: To describe a suture-free technique for canine ureteral resection-anastomosis using a microvascular anastomotic system (MAS) and to compare surgical time and burst pressure of hand-sewn (HS) ureteral end-to-end anastomosis with the MAS technique.

Study Design: Experimental ex vivo study.

Animals: Canine cadavers (n = 8).

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Objective: To determine clinical findings and outcomes for cats and dogs with peritoneopericardial diaphragmatic hernia (PPDH) treated surgically or nonsurgically.

Design: Retrospective case series.

Animals: 28 dogs and 30 cats.

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Objective: To evaluate the safety and efficacy of an adjustable artificial urethral sphincter (AUS) in a population of dogs with acquired or congenital urinary incontinence.

Study Design: Case series.

Animals: Dogs (n = 27) with naturally occurring urinary incontinence.

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Ureteral ectopia is a well-described cause of urinary incontinence in female dogs, but this condition has not been completely characterized in male dogs. Sixteen male dogs with ectopic ureters were evaluated between Jan 1999 and Mar 2007. Male dogs were similar to female dogs with ectopic ureters in terms of breed, presenting complaint, age of onset, and bilateral nature of the ectopia.

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Objective: To evaluate the effects of epsilon aminocaproic acid (EACA) on the prevalence of postoperative bleeding in retired racing Greyhounds (RRG), and to assess its effects on selected thrombelastography (TEG) and fibrinolysis variables.

Study Design: Double-blinded, prospective, randomized study.

Methods: 100 RRG had elective ovariohysterectomy or orchiectomy and were administered EACA or placebo for 3 days after surgery.

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Objectives: To determine the frequency of delayed postoperative bleeding in retired racing Greyhounds with appendicular bone tumors undergoing limb amputations. To identify if administration of epsilon-aminocaproic acid (EACA) was effective on the prevention of postoperative bleeding.

Design: Retrospective study from December 2003 to December 2008.

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Surgical procedures of the lower urinary tract are commonly performed in small animal practice. Cystotomy for removal of uroliths and urethrostomy diverting urine outflow due to urethral obstruction are the most commonly performed surgical procedures of the bladder and urethra respectively. Surgical procedures of the lower urinary tract are typically associated with few complications, including leakage of urine, loss of luminal diameter (stricture or stenosis), urine outflow obstruction, tissue devitalization, denervation, urinary incontinence, urinary tract infection, and death.

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A 6-year-old, spayed female Labrador retriever was presented with clinical signs of stranguria, pollakiuria, and hematuria of 12 weeks' duration. A bacterial urinary tract infection, diffuse polypoid cystitis, and emphysematous cystitis were diagnosed. Antibiotic therapy combined with extensive resection of the mucosa and submucosa associated with polypoid lesions resulted in complete resolution of clinical signs and resolution of the remaining polypoid lesions.

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Urinary incontinence--loss of voluntary control over the retention and expulsion of urine--is a common medical problem in small animal patients. Incontinence occur when pressure within the bladder exceeds urethral pressure. Incontinence may result from a variety of etiologies, including congenital anatomic abnormalities of the lower urinary and reproductive systems (ureter, bladder, bladder neck, urethra, vagina,vestibule) as well as neurologic, neoplastic, infectious, and inflammatory disease.

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Through the reduction of live animal use in teaching surgical technique, the opportunities to deliberately study complex regional anatomy and practice surgical technique have decreased. With reduced exposure, there is concern some individuals are graduating without the requisite knowledge and proficiency to perform adequate surgical techniques. Ultimately, animals may unnecessarily suffer due to morbidities from limited or poor surgical competencies.

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