Publications by Mary Margaret Zablocki

Publications by authors named "Mary Margaret Zablocki"

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Discovery of novel biaryl sulfonamide based Mcl-1 inhibitors.

Bruce Follows Shawn Fessler Timm Baumeister Ann-Marie Campbell Mary Margaret Zablocki

Bioorg Med Chem Lett

August 2019

Mcl-1 is an anti-apoptotic protein overexpressed in hematological malignancies and several human solid tumors. Small molecule inhibition of Mcl-1 would offer an effective therapy to Mcl-1 mediated resistance. Subsequently, it has been the target of extensive research in the pharmaceutical industry.

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