Synopsis of recent research by authors named "Mary Machulda"
Mary Machulda's recent research focuses on the interplay between neurodegenerative diseases, particularly Alzheimer's disease, and various biomarkers, including amyloid PET imaging and cerebrospinal fluid (CSF) analysis, to improve early detection and understanding of disease progression.
Her studies highlight the association between sleep characteristics, such as slow-wave activity in obstructive sleep apnea, and amyloid accumulation, as well as the need for normative data for remote cognitive assessments to enhance clinical evaluation.
Additionally, Machulda investigates the prevalence and clinical characteristics of progressive language disorders, establishing a comprehensive framework for understanding nonverbal oral apraxia and its correlations with neuroimaging findings in patients with neurodegenerative diseases.