Publications by authors named "Mary Katherine Lawrence"
Article Synopsis
- The PRECISION study assesses the impact of aprocitentan, a dual endothelin receptor antagonist, on blood pressure in patients with resistant hypertension through a three-part, randomized, and blinded design.
- It involves a total of 1965 screened patients, with only 730 being randomized, revealing a significant exclusion rate of 62.8%, primarily due to unmet blood pressure criteria.
- The study aims to show both the initial and long-term blood pressure lowering effects of aprocitentan, highlighting the issue of pseudoresistant hypertension among those referred for treatment.