Publications by authors named "Mary K Lawrence"
Article Synopsis
- The PRECISION study assesses the impact of aprocitentan, a dual endothelin receptor antagonist, on blood pressure in patients with resistant hypertension through a three-part, randomized, and blinded design.
- It involves a total of 1965 screened patients, with only 730 being randomized, revealing a significant exclusion rate of 62.8%, primarily due to unmet blood pressure criteria.
- The study aims to show both the initial and long-term blood pressure lowering effects of aprocitentan, highlighting the issue of pseudoresistant hypertension among those referred for treatment.
Background: Long-term safety and efficacy of AIR((R)) inhaled insulin (Eli Lilly and Co., Indianapolis, IN) (AIR is a registered trademark of Alkermes, Inc., Cambridge, MA) in patients with diabetes and concomitant lung disease remain to be established.
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