An Evaluation of Lymph Node Harvest in Sublobar Resections in a Statewide Quality Collaborative.

Objective: Evaluate the effectiveness of nodal harvest in sublobar resections (SLR) for peripheral non-small cell lung cancer (NSCLC).

Methods: Retrospective review of prospectively collected data for patients who underwent wedge resection (WR) and segmentectomy (SG) for NSCLC from January 2015 to March 2023 at 21 centers within a statewide quality collaborative. The primary end point was the extent of lymph node (LN) harvest defined as ≥ 10 LNs, ≥5 lymph node stations (LNS), or 3 mediastinal LNS and 1 hilar LNS (3/1 LNS).

Identifying Synthetic Lectins from a Competitive Screen for the Detection of Prostate Cancer.

Herein, we report a dual dye competitive screening method for the identification of five boronic acid functionalized synthetic lectins (SLs) that are selective for prostate-associated targets with the goal of detecting and staging prostate cancer. This method uses differently labeled normal (RWEP-1) and diseased (PC3) cell membrane extracts in a competitive binding assay to identify SLs that bind either the cancerous or normal extracts but not both. Subsequent studies examined the efficacy of these new SL hits in an array format to discriminate six prostate cell lines.