Diagnosis and management of hypersensitivity reactions related to common cancer chemotherapy agents.

Objectives: To review clinical hypersensitivity reactions related to common cancer chemotherapy agents and to discuss potential management strategies.

Data Sources: PubMed searches were performed for articles published from 1970 to 2008 regarding hypersensitivity to cancer chemotherapy and related agents using the keywords hypersensitivity, allergy, chemotherapy, platinums, taxanes, asparaginase, epipodophyllotoxins, and procarbazine. Retrieved articles were surveyed for additional citations.