Using mycobacterium cell wall fraction to decrease equine chorionic gonadotropin after abortion.

Background: Equine embryonic loss following the development of endometrial cups delays return to cyclicity due to the production of equine chorionic gonadotropin (eCG). Natural degradation of endometrial cups coincides with an influx of immune cells at 100-120 days of gestation, but therapeutic stimulation of reduced eCG production has been relatively unsuccessful. Recently, we observed an increase in pro-inflammatory cytokine production following the use of the immunostimulant mycobacterium cell wall fraction (MCWF).

Frontotemporal Dementia and Psychiatric Illness: Emerging Clinical and Biological Links in Gene Carriers.

Objective: To describe psychiatric presentations in individuals with genetic mutations causing frontotemporal dementia (FTD).

Design: Case descriptions from five carriers of FTD-related gene mutations with symptoms associated with non-neurodegenerative psychiatric disease.

Setting: A comprehensive research program investigating genetic and non-genetic FTD at the University of California, San Francisco Memory and Aging Center.