Publications by authors named "Mary Freyvogel"
Background: Guideline-consistent treatment (GCT) for inflammatory breast cancer (IBC) includes neoadjuvant chemotherapy (NAC), modified radical mastectomy (MRM), and radiation. We hypothesized that younger patients more frequently receive GCT, resulting in survival differences.
Methods: Using the National Cancer Database (2004-2018), female patients with unilateral IBC (by histology code and clinical stage T4d) were stratified by age (< 50, 50-65, > 65 years).
Background: Neoadjuvant chemotherapy (NCT) is considered more effective in downstaging hormone receptor-positive (HR+) breast cancer than neoadjuvant endocrine therapy (NET), particularly in node-positive disease. This study compared breast and axillary response and survival after NCT and NET in HR+ breast cancer.
Methods: Based on American College of Surgeons Oncology Group (ACOSOG) Z1031 criteria, women age 50 years or older with cT2-4 HR+ breast cancer who underwent NET or NCT and surgery were identified in the National Cancer Database 2010-2016.
Article Synopsis
- A study compared how men and women receive neoadjuvant chemotherapy (NAC) for breast cancer and found that fewer men get this treatment.
- The research looked at 196,027 patients and discovered that 73% of men received chemotherapy compared to 84% of women, with only 26% of men getting NAC versus 45% of women.
- Both men and women had similar outcomes after treatment, but men often had more aggressive surgeries, suggesting that men should be given NAC more often when it's suitable.
Background: As an alternative to traditional wire localization, an inducible magnetic seed system can be used to identify and remove nonpalpable breast lesions and axillary lymph nodes intraoperatively. We report the largest single-institution experience of magnetic seed placement for operative localization to date, including feasibility and short-term outcomes.
Methods: Patients who underwent placement of a magnetic seed in the breast or lymph node were identified from July 2017 to March 2019.
Article Synopsis
- Breast MRI can often find things that aren't really a problem, which is called a false-positive.
- In a study, 10.7% of breast cancer patients had extra findings, mostly in the liver and thoracic cavity.
- These extra findings led to more medical tests and delays, but none were actually related to breast cancer or other serious issues.
Background: Nodal positivity is correlated with a poorer prognosis in breast cancer. A study was composed to compare nodal positivity in patients with single versus multiple lesions found on magnetic resonance imaging (MRI) and mammogram (MMG).
Methods: A retrospective study of breast cancer patients undergoing MRI and MMG was performed.
Article Synopsis
- The study looked at how to check for breast cancer returning in patients who had surgery and reconstruction from 2000 to 2009.
- They found that most cases of cancer returning were detected through clinical exams rather than mammograms.
- The results suggest that regular check-ups by doctors are more reliable for finding cancer than routine mammogram screenings.