Publications by authors named "Mary Evelyn White"
Cancer Gene Ther
November 2024
Article Synopsis
- Caveolin-1 (Cav-1) acts as both a tumor suppressor and promoter, but its specific role in lung metastasis from breast cancer is not well understood.
- Researchers found that knocking out Cav-1 in mammary epithelial cells led to significantly reduced lung metastasis in mouse models of breast cancer.
- The study revealed that Cav-1 influences metastasis through the regulation of integrin α3 (ITGα3), linking it to changes in cell migration and extracellular vesicle secretion.
