Publications by authors named "Mary Claire Doss"
Article Synopsis
- Total kidney volume (TKV) measurement using MRI is important for tracking disease progression in polycystic kidney disease (PKD), and is increasingly used in research with animal models.
- The study introduced a new semiautomatic image segmentation method (SAM), comparing its effectiveness in TKV assessment to other methods like the ellipsoid formula (EM), longest kidney length (LM), and manual contouring (MM).
- Results showed SAM as the most accurate and quickest method for assessing TKV in mice and rats, while MM was the slowest and least efficient, highlighting SAM’s potential for enhancing preclinical PKD studies.