Publications by authors named "Mary C Smolskis"
Background: Effective therapeutics for respiratory viruses are needed. Early data suggest that nitazoxanide (NTZ) may be beneficial for treating acute respiratory viral illness.
Methods: From March 2014 through March 2017, a double-blind, placebo-controlled trial was conducted in 260 participants ≥1 year old hospitalized with influenza-like illness at 6 hospitals in Mexico.
Article Synopsis
- - Acute respiratory infections in children, mainly caused by various viruses, can lead to significant health issues, and this study aimed to assess which viruses pose a higher hospitalization risk for kids with influenza-like illness (ILI).
- - The study analyzed data from 1,486 children aged 5 and younger over a four-year period, finding that 82.6% tested positive for at least one virus, with respiratory syncytial virus (RSV) and rhinovirus/enterovirus being the most common.
- - Results indicated that children infected with RSV and metapneumovirus had the highest likelihood of hospitalization, while those with rhinovirus/enterovirus, parainfluenza, coronavirus, adenovirus, and influenza faced a
Objectives: To assess the reliability, validity, and responsiveness of InFLUenza Patient-Reported Outcome (FLU-PRO©) scores for quantifying the presence and severity of influenza symptoms.
Methods: An observational prospective cohort study of adults (≥18 years) with influenza-like illness in the United States, the United Kingdom, Mexico, and South America was conducted. Participants completed the 37-item draft FLU-PRO daily for up to 14 days.