Publications by authors named "Mary B Hribar"
Article Synopsis
- Some people with chronic back pain and problems with opioid use don’t get the complete treatment they need.
- The study will test if providing yoga and physical therapy at places that help with opioid addiction can improve pain and overall well-being.
- They'll randomly assign 345 people to either do yoga, physical therapy, or just get regular treatment for 12 weeks and see if these activities make a positive difference.
Low-Dose Buprenorphine Initiation for Hospitalized Patients With Chronic Pain and Opioid Use Disorder or Opioid Misuse: Protocol for an Open-Label, Parallel-Group, Effectiveness-Implementation Randomized Controlled Trial.
Subst Use Addctn J
January 2025
Buprenorphine is an effective medication for both opioid use disorder (OUD) and chronic pain (CP), but transitioning from full opioid agonists to buprenorphine, a partial opioid agonist, can be challenging. Preliminary studies suggest that low-dose buprenorphine initiation can overcome some challenges in starting treatment, but no randomized controlled trials have compared low-dose and standard buprenorphine initiation approaches regarding effectiveness and safety or examined implementation in hospital settings. In a pragmatic open-label hybrid type I effectiveness-implementation trial based in a single urban health system, 270 hospitalized patients with (a) CP and (b) OUD or opioid misuse are being randomized to buprenorphine treatment initiation using 5-day low-dose or standard initiation protocols.
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