Publications by authors named "Mary Ann Woodroffe"
Ann Intern Med
September 2002
Article Synopsis
- Methadone is a well-known treatment for opioid dependency and chronic pain, but concerns were raised after a related drug, levacetylmethadol, was linked to torsade de pointes, a type of heart arrhythmia.
- A study analyzed 17 patients who were treated with high doses of methadone and experienced torsade de pointes, observing their health records for risk factors and heart activity.
- Results indicated that these patients had significantly high doses of methadone and prolonged QT intervals, highlighting potential risks associated with high-dose methadone and suggesting a need for further research, especially as methadone use expands in primary care.
