Silence of the lungs: comparing measures of slow and noncommunicating lung units from pulmonary function tests with computed tomography.

Multiple breath washout (MBW) has successfully assessed the silent lung zone particularly in cystic fibrosis lung disease, however, it is limited to the communicating lung only. There are a number of different pulmonary function methods that can assess what is commonly referred to as trapped air, with varying approaches and sensitivity. Twenty-five people with cystic fibrosis (pwCF) underwent MBW, spirometry, body plethysmography, and spirometry-controlled computed tomography (spiro-CT) on the same day.

Migration is not the perfect answer: How the cross-talk error correction for multiple breath nitrogen washout (MBWN ) parameters differs on directly collected vs. legacy data.

Recently, a cross-talk error with commercial multiple breath nitrogen washout (MBWN ) software was discovered, which produced an absolute over-reading of N of approximately 1%, i.e., 2% N read as 3%.