panniculitis in a cat from northern California.

Case Summary: A 9-year-old male castrated domestic shorthair cat from northern California was evaluated for a 12-month history of dermal and subcutaneous dermatitis in the inguinal region. Histopathologic examination of a biopsy revealed severe, chronic, multifocal to coalescing pyogranulomatous dermatitis and panniculitis, accompanied by ulceration and central necrosis. Aerobic bacterial culture of lesions yielded mycobacterial growth.

Safety profile and effects on the peripheral immune response of fecal microbiota transplantation in clinically healthy dogs.

Background: Fecal microbiota transplantation (FMT) is increasingly used for gastrointestinal and extra-gastrointestinal diseases in veterinary medicine. However, its effects on immune responses and possible adverse events have not been systematically investigated.

Hypothesis/objectives: Determine the short-term safety profile and changes in the peripheral immune system after a single FMT administration in healthy dogs.

Polyautoimmunity manifest as inflammatory myopathy, uveitis, and progressive cutaneous depigmentation in a mixed breed dog: a case report.

Background: Polyautoimmunity is the expression of more than one autoimmune disease in a single patient. This report documents polyautoimmunity in a mixed breed dog with concurrent uveitis, cutaneous depigmentation, and inflammatory myopathy.

Case Presentation: A 1-year-old male neutered mixed breed dog was presented for progressive generalized leukotrichia and leukoderma, bilateral panuveitis, and masticatory muscle atrophy.

Alterations in common marmoset gut microbiome associated with duodenal strictures.

Chronic gastrointestinal (GI) diseases are the most common diseases in captive common marmosets (Callithrix jacchus). Despite standardized housing, diet and husbandry, a recently described gastrointestinal syndrome characterized by duodenal ulcers and strictures was observed in a subset of marmosets sourced from the New England Primate Research Center. As changes in the gut microbiome have been associated with GI diseases, the gut microbiome of 52 healthy, non-stricture marmosets (153 samples) were compared to the gut microbiome of 21 captive marmosets diagnosed with a duodenal ulcer/stricture (57 samples).

Analysis of gut microbiome profiles in common marmosets (Callithrix jacchus) in health and intestinal disease.

Chronic gastrointestinal (GI) diseases are the most common diseases in captive common marmosets. To understand the role of the microbiome in GI diseases, we characterized the gut microbiome of 91 healthy marmosets (303 samples) and 59 marmosets diagnosed with inflammatory bowel disease (IBD) (200 samples). Healthy marmosets exhibited "humanized," Bacteroidetes-dominant microbiomes.

Detection of in Fur Swab and Fecal Samples by Using PCR Analysis.

Current methods for detecting mites in mouse colonies have limitations in terms of cost, accuracy, and throughput. To address these limitations, we developed PCR assays to detect in fecal samples. Using a newly generated ribosomal RNA sequence of (MC28S), we developed PCR and qPCR assays capable of detecting mites or eggs ingested during grooming.

Asthma surveillance using Medicaid administrative data: a call for a national framework.

Connecticut, Michigan, and New York have successfully used Medicaid administrative data to conduct surveillance of asthma prevalence, related health service utilization and costs, and quality of asthma care. Since these assessments utilize beneficiary-level data, a wide range of population-based summaries is feasible. Opportunities exist to build upon the collective experiences of these three states to establish a national framework for asthma surveillance using Medicaid administrative data.

Variation in emergency department wait times for children by race/ethnicity and payment source.

Objective: To quantify the variation in emergency department (ED) wait times by patient race/ethnicity and payment source, and to divide the overall association into between- and within-hospital components.

Data Source: 2005 and 2006 National Hospital Ambulatory Medical Care Surveys.

Study Design: Linear regression was used to analyze the independent associations between race/ethnicity, payment source, and ED wait times in a pooled cross-sectional design.

Impact of mandatory physician reporting on accident risk in epilepsy.

Background: In some jurisdictions, physicians are required by law to report patients with seizures to the department of motor vehicles. We assessed the hypothesis that mandatory reporting reduces the risk of automobile accidents in people with epilepsy.

Methods: A retrospective survey of driving and accident rates was done by mailed questionnaire to two groups of subjects with epilepsy in Canada, one living in Ontario where reporting is mandatory and the other in Alberta where it is not.

Childhood injuries in Connecticut's Medicaid managed care program.

This study describes childhood injuries and injury-related care using encounter data from a Medicaid managed care program. Enrollment and encounter data for federal fiscal year 2000 were used to identify children who received treatment for an injury, to identify risk factors, and to describe injury-related care. Twenty percent of children were treated for an injury.

Well-baby care in Connecticut's Medicaid managed-care program.

Objectives: 1) To describe well-baby care in Connecticut's Medicaid managed-care program; 2) to determine the effect of well-baby care on emergency care or hospitalization for ambulatory care-sensitive conditions.

Design: Retrospective cohort study.

Methods: Babies born between January 1 and March 31, 2000 who were continuously enrolled for the first year of life were identified (n = 2,054).

Historical criteria that distinguish syncope from seizures.

Objectives: We prospectively sought evidence-based criteria that distinguished between seizures and syncope.

Background: Loss of consciousness is usually due to either seizures or syncope. There are no evidence-based historical diagnostic criteria that distinguish them.

Optimizing epilepsy surgery with intraoperative MR imaging.

Purpose: The surgical treatment of medically intractable temporal lobe epilepsy includes the resection of temporal lobe structures. Although the reported seizure-free outcomes are highly variable, there is growing evidence that the extent of resection of the mesiotemporal lobe directly correlates with seizure control.

Methods: A moveable, high-field intraoperative magnetic resonance (MR) system was used to monitor and optimize the resection of the amygdala and hippocampus in 14 epilepsy patients.