Publications by Marwan E Simaan

Publications by authors named "Marwan E Simaan"

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Clickable Cisplatin Derivatives as Versatile Tools to Probe the DNA Damage Response to Chemotherapy.

Amandine Moretton Jana Slyskova Marwan E Simaan Emili A Arasa-Verge Mathilde Meyenberg

Front Oncol

June 2022

Cisplatin induces DNA crosslinks that are highly cytotoxic. Hence, platinum complexes are frequently used in the treatment of a broad range of cancers. Efficiency of cisplatin treatment is limited by the tumor-specific DNA damage response to the generated lesions.

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