Efficacy and safety of oral mega pulse methylprednisolone for severe therapy resistant Alopecia areata.

Objective: To use intensive regimen of pulse steroid in the severe forms of Alopecia areata.

Methods: This prospective randomized study was conducted at King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia between 2003 to 2009. Patients with Alopecia universalis, Alopecia totalis, or Alopecia ophiasis were assigned to one of the 3 treatment groups: Group A received oral mega pulse methylprednisolone (MP) for 3 consecutive days once every 2 weeks for 24 weeks; Group B received 2 consecutive daily pulses every 3 weeks; and Group C received 3 consecutive daily pulses every 3 weeks.

Treatment of linear IgA bullous dermatosis of childhood with flucloxacillin.

Background: Linear IgA bullous dermatosis of childhood is a rare autoimmune bullous disease that mainly affects preschool-aged children. Dapsone is considered the first-line therapy with prompt response from most patients. However, it may be contraindicated in certain conditions such as glucose-6-phosphate dehydrogenase deficiency.

Finasteride for hirsutism: a dose finding study.

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