Choice of Intravenous Crystalloid Fluid and Mortality in Critically Ill Adult Patients.

Objectives: Intravenous balanced crystalloid fluid therapy may improve mortality and other outcomes in critically ill adult patients, but data are conflicting. We conducted a meta-analysis and literature review to evaluate the impact of intravenous balanced crystalloid, as compared with normal saline, fluid therapy on outcomes in critically ill adult patients.

Methods: We searched PubMed, Scopus, MEDLINE, and the Cochrane Register of Clinical Trials for relevant studies.