This study explores how gamma radiation affects DNA concentration and the stability of autosomal short tandem repeat (STR) markers in buccal swab samples. A total of 160 swabs from 20 volunteers were exposed to therapeutic radiation doses ranging from 1 to 80 Gy. The results revealed a clear dose-dependent decrease in DNA concentration, indicating significant DNA damage as radiation increased.
View Article and Find Full Text PDFThis study aims to introduce national diagnostic reference levels (NDRLs) for adult hybrid single photon emission computed tomography (SPECT-CT) in nuclear medicine (NM) departments in the Kingdom of Saudi Arabia. The administered activity (AA) of radiopharmaceuticals, volume-weighted computed tomography dose index (CTDI) and dose length product (DLP) for ten hybrid SPECT/CT examinations were collected and analysed for one year. The median of AA, CTDIand DLP for each dose quantity was derived and the suggested national DRLs were determined based on the 75percentile for all identified SPECT-CT examinations.
View Article and Find Full Text PDF