A functional SNP in miR-146a and genetic susceptibility to drug-resistant epilepsy.

Objectives: The study aimed to assess the relationship between the functional single nucleotide polymorphism (SNP) (rs57095329) of miR-146a, the progression of drug-resistant epilepsy (DRE), and the severity of the disease (seizure frequency) in a group of Egyptian children epilepsy patients.

Subjects And Methods: 110 Egyptian children were recruited and divided into two groups, the epilepsy patients ( = 60) and the healthy control children ( = 50). The patient's group was equally subdivided into two subgroups: drug-resistant and drug-responsive epilepsy patients.

Serum interleukin 1β and sP-selectin as biomarkers of inflammation and thrombosis, could they be predictors of disease severity in COVID 19 Egyptian patients? (a cross-sectional study).

Background: Thromboembolism was a chief cause of mortality in 70% of patients with COVID-19. Our objective was to see if serum interleukins 1 beta (IL-1β) and soluble platelets selectin (sP-selectin) could serve as novel markers of thromboembolism in COVID-19 patients.

Methods: This cross sectional study involved 89 COVID-19 patients who were recruited from 1st of February to 1st of May 2021.

Purification and Characterization of Ornithine Decarboxylase from ; Kinetics of Inhibition by Various Inhibitors.

l-Ornithine decarboxylase (ODC) is the rate-limiting enzyme of polyamine synthesis in humans and fungi. Elevated levels of polyamine by over-induction of ODC activity in response to tumor-promoting factors has been frequently reported. Since ODC from fungi and human have the same molecular properties and regulatory mechanisms, thus, fungal ODC has been used as model enzyme in the preliminary studies.

The prevalence of chlamydia trachomatis among patients with acute conjunctivitis in Kasr Alainy ophthalmology clinic.

Introduction: Trachoma is a leading cause of avoidable blindness and endemic conjunctivitis in 57 countries. It infects approximately 84 million people globally, and continues to threaten over 10% of the world's population with the risk of blindness.

Methods: This is a cross sectional descriptive study assessing patients presenting with acute conjunctivitis.