Publications by authors named "Marwa Helmy Abdallah"
Article Synopsis
- The study focused on creating a new drug delivery system using biotinylated chitosan (Bio-Chi) on multi-walled carbon nanotubes (MWCNTs) to improve breast cancer treatment with neratinib (NT).
- Bio-Chi provided two targeting strategies: a pH-sensitive release mechanism and active targeting through biotin, which enhanced drug uptake by cancer cells.
- The results showed that NT-loaded Bio-Chi-coated c-MWCNTs significantly improved drug delivery efficiency and cytotoxicity against breast cancer cells compared to free NT or NT-loaded naked c-MWCNTs.
Among the various types of cancer, lung cancer accounts for the highest number of fatalities across the globe. A combination of different cancer chemotherapeutics is regarded as an effective strategy for clinical management of different cancers. Ganetespib (GAN) is a well-established hsp90 inhibitor with enhanced pharmacological properties in comparison with its first-generation counterparts.
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