The study aimed to compare two methods—chromocolonoscopy and the Colon Cancer-Specific Antigen-2 (CCSA2) test—for early detection of colorectal cancer (CRC) among Egyptian patients.
It involved 55 participants divided into three groups: those with precancerous lesions, those diagnosed with CRC, and a control group, with various tests conducted, including stool occult blood measurement and serum CCSA2 levels.
Results showed higher CCSA2 levels in CRC patients, with specific cutoff values revealing varying sensitivity and specificity, indicating that both CCSA2 tests and chromoendoscopy are effective for detecting CRC and related conditions.