Publications by authors named "Marwa El-Mohamdy"

Article Synopsis
  • The study looked at the connection between periorbital melanosis (POM), which causes dark circles around the eyes, insulin resistance (IR), and vitamin D levels.
  • Researchers compared 100 patients with POM to 100 healthy people to see how their vitamin D and IR indicators matched up.
  • They found that people with POM had higher IR and lower vitamin D levels, suggesting POM could be a helpful sign for early detection of these health issues.
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Background: Genetic polymorphisms play a crucial role in predicting treatment efficacy in patients with hepatocellular carcinoma (HCC). This study aims to evaluate the response to Transarterial Chemoembolization (TACE) in relation to the genetic polymorphisms of interleukin 28B (IL28B) and angiopoietin-2 (ANGPT2) in HCC patients.

Research Design And Methods: Prospective cohort study conducted on 104 eligible HCC Egyptian patients who underwent TACE using doxorubicin and lipiodol.

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Article Synopsis
  • This study investigated the effectiveness and safety of Infliximab (IFX) and Adalimumab (ADA) in treating moderate to severe Inflammatory Bowel Disease (IBD), focusing on Ulcerative Colitis (UC) and Crohn's Disease (CD).
  • It involved 56 patients, with improvements measured in Crohn's Disease Activity Index (CDAI), Mayo Score/Disease Activity Index (DAI), and C-reactive protein (CRP) levels after 14 weeks of treatment, showing significant reductions for both medications.
  • The findings indicate that both IFX and ADA provide effective treatment and have a strong safety profile, with higher drug concentrations linked to better
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Multiple sclerosis (MS) is a multifactorial polygenic disease; results from autoimmune and neurodegenerative processes which lead to multifocal lesions of the central nervous system. Axonal degeneration was found to be prominent in the inflammation period of MS and contribute to the progression of disability. Soluble N-ethylmaleimide sensitive factor attachment receptor (SNARE) complex plays a vital role in the release of neurotransmitter by synaptic vesicle fusion.

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In view of the rapid spread of COVID-19 and the high mortality rate of severe cases, reliable risk stratifying indicators of prognosis are necessary to decrease morbidity and mortality. The aim of the present study was to evaluate the value of serum amyloid A (SAA) and carcinoembryonic antigen (CEA) as prognostic biomarkers in comparison to other predictors, including C-reactive protein (CRP) and ferritin levels. This study included 124 patients diagnosed with COVID-19, and they were assigned to one of two groups: Mild and severe, based on the severity of the infection.

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