Publications by authors named "Marwa El Khalifa"
Background: Eye lesions, occur in nearly half of patients with Behçet's Disease (BD), can lead to irreversible damage and vision loss; however, limited studies are available on identifying risk factors for the development of vision-threatening BD (VTBD). Using an Egyptian college of rheumatology (ECR)-BD, a national cohort of BD patients, we examined the performance of machine-learning (ML) models in predicting VTBD compared to logistic regression (LR) analysis. We identified the risk factors for the development of VTBD.
View Article and Find Full Text PDFBackground: Metabolic syndrome (MetS) is characterized by insulin resistance, high blood pressure/ sugar, dyslipidemia, and obesity. Whether MetS and its components affect the development of Behçet's Disease (BD) remains unclear.
Aims: The aim was to determine the frequency of MetS among BD patients and to study its relationship with disease characteristics.
Objectives: This study aims to present the manifestations of juvenile systemic lupus erythematosus (JSLE) across Egypt, to focus on age at onset and gender-driven influence on disease characteristics, and to compare findings to other countries.
Methods: The study included 404 Egyptian children with systemic lupus erythematosus (SLE) presenting to one of the specialized rheumatology centers corresponding to 13 major governorates. Juvenile cases age was ≤ 16°years at the time of recruitment.
Background: Behçet's disease (BD) is a chronic multisystem variable vessel vasculitis. Disease damage is irreversible and permanent. Validated tools evaluating damage are limited.
View Article and Find Full Text PDFArticle Synopsis
- The study examined the attitudes of Egyptian rheumatology staff regarding the COVID-19 vaccine through a 25-question survey, which included adapted questions from a global alliance survey.
- About 187 staff members participated, with a majority being female; findings revealed that only one-third were ready to be vaccinated, while a significant portion expressed hesitance or refusal.
- The study highlights concerning levels of vaccine acceptance among healthcare providers, suggesting a need for targeted interventions to reduce vaccine hesitancy and improve access for patients with rheumatic diseases in Egypt.
Objective: The aim of this study was to present the epidemiology, clinical manifestations and treatment pattern of systemic lupus erythematosus (SLE) in Egyptian patients over the country and compare the findings to large cohorts worldwide. Objectives were extended to focus on the age at onset and gender driven influence on the disease characteristics.
Patients And Method: This population-based, multicenter, cross-sectional study included 3661 adult SLE patients from Egyptian rheumatology departments across the nation.
The author wishes to correct the record and clarify that in the original version of this article in the Discussion section under "Prevalence over the country governorates" inadvertently presented incorrect data cited in the reference [30].
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- The study estimates the prevalence of Behçet's disease (BD) in adults in Egypt at 3.6 cases per 100,000, with higher rates in Alexandria and Cairo.
- The research involved 1,526 patients from 26 rheumatology centers, examining demographic and clinical data, revealing a male-to-female ratio of approximately 2.6:1 and highlighting various co-morbidities.
- Findings indicated that disease characteristics varied between males and females, affecting clinical manifestations such as central nervous system involvement, joint issues, and overall disease activity.