Publications by authors named "Marwa Ayadi"
Article Synopsis
- * A specific reaction described is the Luche reduction of a primary phosphonate, leading to the formation of γ-hydroxyallylphosphonates, which subsequently react with tosylamines to produce S2-type products with yields of 63 to 70%.
- * The method also allows for the conversion of the resulting alcohol to an acetate, which can be transformed into γ-aminoallylphosphonates using cerium (Ce
Under solvent-free conditions and at 80 °C, a DMAP- or imidazole-mediated clean and rapid conversion of cyclic Morita-Baylis-Hillman (MBH) acetates into the corresponding γ-keto allyl phosphonates in 70-93% yields is described herein. This allylic nucleophilic substitution works well with primary and secondary acetates bearing, at the β'-position, linear or branched alkyl groups and aryl groups.
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