Publications by authors named "Marwa Ahmed Mahmoud"
The reproductive system of males is adversely impacted by lead (Pb), a toxic heavy metal. The present study examined arbutin, a promising hydroquinone glycoside, for its potential ameliorative impact against Pb-induced testicular impairment in rats. The testicular injury was induced by the intraperitoneal administration of Pb acetate (20 mg/kg/day) for 10 consecutive days.
View Article and Find Full Text PDFBackground: Extreme body mass index (BMI) is an influential pathophysiological risk factor for serious illnesses following lower respiratory tract infection. The purpose of the current study was to examine how the BMI of Coronavirus disease-19 (COVID-19) patients affects their prognosis.
Methods: Two hundred patients with COVID-19 admitted to Al-Azhar, Qena, Aswan, and Sohag University hospitals in Egypt were included and categorized into four groups according to their BMI.
Article Synopsis
- The study aimed to investigate how the MIF gene polymorphism rs755622 G>C influences the development and severity of hepatocellular carcinoma (HCC) in Egyptian patients.
- It included 50 HCC patients and 50 healthy individuals, analyzing data through various scoring systems and genetic testing.
- Results revealed that specific genotypes (GG and GC) of the MIF gene occurred more frequently in HCC patients, particularly those with advanced liver disease, indicating a potential link between this genetic variant and HCC progression.
Peripheral Mononuclear Cells Surface Markers Evaluation in Different Stages of Hepatocellular Carcinoma; in a Trial for Early and Accurate Diagnosis in Patients with Post-Hepatitis Liver Cirrhosis and Unremarkable Raised AFP.
Int J Gen Med
March 2023
Introduction: HCC is frequently diagnosed late, when only palliative treatment is available. So, we try to use different immunological markers to identify early HCC in patients with unremarkable raised AFP.
Methods: This study was conducted on 112 participants divided into two equal groups: Group I, 56 patients with liver cirrhosis and different stages of HCC; Group II, 56 patients with liver cirrhosis.
Antitoxic Effects of Curcumin against Obesity-Induced Multi-Organs' Biochemical and Histopathological Abnormalities in an Animal Model.
Evid Based Complement Alternat Med
October 2022
Article Synopsis
- Obesity leads to increased oxidative stress and inflammation, impacting organs like the liver, duodenum, and heart, particularly due to a high-fat diet in rats.
- The study involved three groups of rats: a control group, a high-fat diet group, and a high-fat diet group supplemented with curcumin, examining changes in glucose, insulin levels, and histological conditions.
- Results showed that the high-fat diet caused significant biochemical abnormalities and inflammation, while curcumin treatment notably improved these conditions, suggesting its potential as a therapeutic agent against obesity-related complications.
Osteoarthritis (OA) etiology and pathogenesis not yet fully understood. We studied the role of vitamin D receptor single-nucleotide polymorphisms (VDR-SNPs), vitamin D3, serum and synovial macrophage migration inhibitory factor (MIF), and tumor necrosis factor-α (TNF-α) in the development and progression of knee OA (KOA). This study included 205 Egyptian subjects (105 patients with KOA and 100 unrelated, healthy matched subjects selected as controls).
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