This study aimed to evaluate the toxicological effects of oral intake of Zinc oxide nanoparticles (ZnO NPs) on the structure of thymus and spleen. Twenty-four young male Wistar albino rats were assigned into two groups: group I (control) and group II (ZnO NPs treated group).The thymus and spleen were analyzed biochemically, histopathologically and immunohistochemically.
View Article and Find Full Text PDFCarbon monoxide (CO) poisoning is a leading cause of toxicity-related mortality and morbidity worldwide. Recent studies focused on CO-induced cardiovascular toxicity. Oxidative stress plays an important role in the pathophysiology of CO toxicity.
View Article and Find Full Text PDFAtrazine (ATZ) is one of the most commonly used herbicides contaminating plants, soil and water resources. Several strategies have been used to counteract ATZ toxicity. Here, we tested the hypothesis that lycopene could ameliorate ATZ-induced toxicity in the adrenal cortex.
View Article and Find Full Text PDFIntroduction: effective communication in a clinical environment plays a vital role in patient assessment and treatment. The aim of this study was to understand the experiences of Malaysian medical students concerning communication barriers during clinical practice. The goal was to provide answers for three important research questions, i.
View Article and Find Full Text PDFHistological and biochemical alterations induced in prostate by cypermethrin insecticide exposure were investigated in adult albino rats. 60 mg/kg/day of cypermethrin were given orally to experimental group for 15 days then prostatic specimens were processed for light and electron microscopic examinations and for assessment of oxidative stress markers; prostatic glutathione (GSH), glutathione peroxidase enzyme (GPx) and malondialdehyde (MDA). Masson's trichrome and anti-α-actin antibodies immunohistochemical staining were done.
View Article and Find Full Text PDFObjectives: Exposure to certain environmental toxins may be associated with increased risk of developing diabetes mellitus. The aim of the present study was to investigate the relation between chronic exposure to malathion and insulin resistance among farmers.
Design And Methods: The study included 98 non diabetic farmers who handle agricultural insecticides during their field work.
Benzodiazepines belongs to one of the most commonly used anxiolytic and anticonvulsant drugs in the world. Full description of toxic effects on different organs is lacking for nearly all the current benzodiazepines. The aim of the current work was to study the immunologic and vascular changes induced by sub-chronic administration of alprazolam and clonazepam in non-stressed and stressed adult male albino rats.
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