Prospective studies indicate that direct anticoagulants, rivaroxaban and apixaban, are safe and effective when used during radiofrequency ablation (RFA) for atrial fibrillation (AF), though no comparative studies exist.
A study of 358 patients revealed no significant differences in outcomes or complications between those taking apixaban and those on rivaroxaban during the procedure.
Results show low rates of thromboembolic events and pericardial effusions for both medications, affirming that their uninterrupted use during AF RFA is safe and comparable.