Poorly Differentiated Thyroid Carcinoma Coexisting with Graves' Disease Involving T3 Thyrotoxicosis due to Increased D1 and D2 Activities.

Poorly differentiated thyroid carcinoma is rare and patients are typically euthyroid. We report a novel rare case of poorly differentiated thyroid carcinoma with triiodothyronine (T3) thyrotoxicosis. A 77-year-old man presented to Kuma Hospital due to a neck tumor.

Mite control effect of branched chain fatty acid on the house dust mite Dermatophagoides pteronyssinus.

House dust mites, Dermatophagoides pteronyssinus are present in the indoor environments, such as pillows and carpets. In this study, we investigated the mite control effect of branched chain fatty acids (2-ethylhexanoic acid (iso-C8), 2-butyloctanoic acid (iso-C12), isopalmitic acid (iso-C16) and their mechanism of action. These fatty acids showed a higher acaricidal activity than the straight chain fatty acids.

Endocrinological Features of Hartsfield Syndrome in an Adult Patient With a Novel Mutation of .

Hartsfield syndrome (HS: OMIM 615465) is a rare congenital disease associated with a mutation of the gene () with the main features of holoprosencephaly and ectrodactyly. Patients with HS also present with endocrinological deficits, such as isolated hypogonadotropic hypogonadism and central diabetes insipidus. Although there are several studies on infancy/childhood history, there is no study of infant/childhood/adolescent/young adult HS natural history and endocrinological findings.

Development and Implementation of a Subcutaneous Insulin Pen Label Bar Code Scanning Protocol to Prevent Wrong-Patient Insulin Pen Errors.

Problem Definition: Insulin, a high-alert medication, is regularly prescribed in the inpatient setting for hyperglycemia and diabetes mellitus. Although convenient, insulin pens carry a risk of blood-borne pathogens if the same pen is used on multiple patients. At the University of California, San Francisco (UCSF), a new nursing protocol for insulin pen administration was developed to ensure that insulin was quickly available and to identify and move to eliminate wrong-patient insulin pen errors.

Decreasing triage time: effects of implementing a step-wise ESI algorithm in an EHR.

Objectives: To determine if adapting a widely-used triage scale into a computerized algorithm in an electronic health record (EHR) shortens emergency department (ED) triage time.

Design: Before-and-after quasi-experimental study.

Setting: Urban, tertiary care hospital ED.

Preoperative evaluation of submucosal invasive colorectal cancer using a 15-MHz ultrasound miniprobe.

Background And Study Aims: Recently, it was reported that focal submucosal invasive colorectal cancer could be treated by polypectomy or endoscopic mucosal resection (EMR) because of the rarity of lymph-node metastasis. Our objective was to examine the accuracy and efficacy of a 15-MHz ultrasound miniprobe in the preoperative evaluation of the degree of submucosal invasion in colorectal cancer.

Patients And Methods: A total of 35 patients with submucosal invasive colorectal cancer who underwent ultrasonography with a miniprobe were studied prospectively.

Pathological appearance of the stomach after endoscopic mucosal resection for early gastric cancer.

Background: The pathological findings of the resected stomach after endoscopic mucosal resection (EMR) for early gastric cancer were reviewed. EMR was indicated when a lesion consisting of well or moderately differentiated adenocarcinoma had a diameter of less than 2 cm.

Methods: Of 39 patients with early gastric cancer were treated with EMR between 1990 and 1995, 11 required additional surgery.

Endoscopic ultrasonography: a promising method for assessing the prospects of endoscopic mucosal resection in early gastric cancer.

Background And Study Aims: A recent challenge that is increasingly being faced in endoscopy is the use of endoscopic mucosal resection (EMR) to treat differentiated intramucosal gastric cancers smaller than 2 cm. The usefulness of pretherapeutic endoscopic ultrasonography (EUS) in assessing whether this form of treatment is possible remains controversial.

Patients And Methods: We retrospectively investigated the value of pretherapeutic EUS evaluation in 58 patients with macroscopically early gastric cancer that was histologically differentiated and less than 2 cm in diameter.

Endoscopic ultrasonographic evaluation of gastric ulcer healing on treatment with proton pump inhibitors versus H2-receptor antagonists.

Background: It has been reported that time to peptic ulcer healing is shorter with proton pump inhibitors (PPI) than with H2-receptor antagonists (H2-RA). This study was designed to examine the difference in the healing process between gastric ulcers treated with PPI and those treated with H2-RA.

Methods: The healing of deep gastric ulcers treated with PPI (n = 11) or H2-RA (n = 13) was evaluated with endoscopic ultrasonography (EUS).

Experimental studies on a new bioactive bone cement: hydroxyapatite composite resin.

We developed hydroxyapatite composite resin (CAP) as a new type of bioactive bone cement. CAP is composed of 80% w/w hydroxyapatite granules (mean particle size: 2 microns) and bis-phenol-A glycidyl methacrylate-based resin. The setting time is 5 min and the peak curing temperature during polymerization is 46 degrees C.

Evaluation of acetic acid-induced gastric ulcers in dogs by endoscopic ultrasonography.

To clarify the ability of endoscopic ultrasonography (EUS) to diagnose gastric ulcer, we induced gastric ulcer (19 open ulcers and 11 ulcer scars) by injecting acetic acid into the stomach via an endoscope in 15 dogs. The stomachs were resected and scanned by EUS in a water bath, and the findings were compared with the histologic observations. The ulcer depth was correctly diagnosed in 29 of 30 instances (96.

Rectal carcinoid tumor: endoscopic ultrasonographic detection and endoscopic removal.

Eight patients with rectal carcinoid tumors were examined by endoscopic ultrasonography (EUS) to assess the depth of invasion of the rectal wall. All resected tumors were contained within the submucosa and their depth of invasion was correctly diagnosed by EUS before treatment. Perirectal lymph nodes were not delineated by EUS.

Pubic-type dislocation of the hip combined with fracture of the ipsilateral greater trochanter. A case report.

Traumatic anterior dislocation of the hip is a relatively uncommon injury, and when it does occur it is frequently combined with osteochondral fracture of the femoral head or the acetabulum. Anterior dislocation of the hip with an associated fracture of the ipsilateral greater trochanter is extremely rare. This paper presents a case of this rare type of injury and clarifies the mechanism of the injury using a cadaver specimen.

Scirrhous carcinoma of the stomach versus hypertrophic gastritis: findings at endoscopic US.

To differentiate scirrhous carcinoma from hypertrophic gastritis, 16 patients with scirrhous carcinoma of the stomach and seven patients with hypertrophic gastritis were examined with endoscopic ultrasonography (US) between August 1987 and October 1990. US images of the normal gastric walls of 16 patients with gastric ulcers served as controls. Characteristic features of scirrhous carcinoma included an irregular hypoechoic enlargement of the third (submucosa) and fourth (muscularis propria) layers.

Staging and follow-up of primary gastric lymphoma by endoscopic ultrasonography.

The usefulness of endoscopic ultrasonography (EUS) was assessed for diagnosing the depth of invasion in the gastric wall, the infiltration to the adjacent organs, and detecting regional lymph node involvement in primary gastric lymphoma. EUS was performed in 11 patients with primary gastric lymphoma who subsequently underwent gastrectomy with lymph node dissection, as well as chemotherapy in some cases. EUS findings showed a good correlation with the histopathology of the resected specimens.

Preoperative evaluation of gastric cancer by endoscopic ultrasound.

The preoperative use of endoscopic ultrasound was evaluated in 74 patients with confirmed gastric cancer. It was used in diagnosing the depth of invasion in the gastric wall, the infiltration to the adjacent organs, and the involvement of the perigastric lymph nodes. Results were compared with histological findings in resected specimens.

[Familial scapuloperoneal-type myopathy associated with a marked elevation of serum creatine kinase and hepatomegaly].

The proband, a 17-year-old boy, was admitted to our department because of the difficulty in standing on heel. Physical examination revealed a marked weakness and atrophy of bilateral lower legs, especially anterior tibial muscles. Patellar and Achilles tendon reflexes were abolished.