Re-emergence of papulonodular napkin dermatitis with use of reusable diapers: report of 5 cases.

The use of reusable diapers, often made of cotton and bamboo material, is becoming more widespread in France--with the "eco" fashion, as they are considered more natural, ecologic and economic. We report 5 cases of papulonodular lesions in convex skin areas associated with the use of these diapers in infants. One case was typical Sevestre and Jacquet erosive dermatitis.

Patients' acceptance of medical photography in a French adult and paediatric dermatology department: a questionnaire survey.

Background: Despite the increasing use of medical photography by dermatologists, no study on patients' perceptions of photography in dermatology has been performed to date.

Objectives: Firstly, to evaluate patients' perceptions of medical photography. Secondly, to assess whether perceptions differed between patients in our adult department and parents accompanying a child in our paediatric department.

Lack of effect of propranolol in the treatment of lymphangioma in two children.

Vascular lesions such as hemangiomas and lymphangiomas can cause significant mortality and morbidity, as well as amblyopia when located in the orbit. Oral propranolol can regress infantile hemangioma during infancy and up to 23 months of age, but its effect on lymphangioma has not been demonstrated. We present two cases of lymphatic malformations treated with oral propranolol.

Effect of physician dress style on patient confidence.

Background: We lack data on how physicians can instill confidence in patients.

Objectives: We aimed to determine whether dress style (professional white coat or formal, semiformal or casual attire) affects confidence in the physician by patients (children, teenagers, adults) with dermatology complaints consulting in the hospital or private practice.

Methods: Design.

Treatment of early-onset Gorham syndrome with 8-year follow-up.

A case of Gorham disease with several years of follow-up is reported. At birth he had a mass in the thigh which was had pathology demonstrating a lymphangioma. By age 3 years, he had lymphedema of the ipsilateral foot and discrepant leg lengths.

Visceral and mucosal involvement in neonatal haemangiomatosis.

Background: Two types of neonatal haemangiomatosis (NH) are distinguished: diffuse which is associated with a high rate of mortality linked to mucosal/visceral involvement, and benign.

Objectives: First, this study aimed to examine the frequency of mucosal and visceral (especially hepatic) involvement in NH, according to skin extension, and second, it aimed to examine clinical, pathological (with glucose transporter 1 (GLUT-1) immunostaining), and imaging features of NH, including follow-up data.

Methods: This was a descriptive retrospective study carried out in the University Hospital Center of Tours, France.

Sturge-Weber syndrome in patients with facial port-wine stain.

Facial port-wine stain (PWS) may be associated with cerebrovascular abnormalities such as Sturge-Weber syndrome (SWS). In a large series, we aimed to assess which topography of facial PWS can predict SWS. This was a cross-sectional study of consecutive patients with facial PWS seen in pediatric dermatologic or angiodysplasia consultations from 1993 to 2005 at the University Hospital Center of Tours.

Tolerance of low-frequency ultrasound sonophoresis: a double-blind randomized study on humans.

Background: Sonophoresis [low-frequency ultrasound (US)] has been used in animals and in vitro to investigate enhanced percutaneous absorption of drugs. No study focused on its clinical human tolerance has been published as yet.

Methods: We aimed to assess the bioeffects of low-frequency US in vivo on human skin in a double-blind randomized-controlled study.

High levels of antibodies against merkel cell polyomavirus identify a subset of patients with merkel cell carcinoma with better clinical outcome.

Purpose: A new human polyomavirus, Merkel cell polyomavirus (MCV), was identified in 2008 in tumor tissue of patients with Merkel cell carcinoma (MCC), a relatively rare human skin cancer. In this study, we investigated patients with MCC and controls for the presence of antibodies against MCV and their association with clinical characteristics.

Patients And Methods: Antibodies against MCV were investigated by enzyme-linked immunosorbent assay in 68 patients with MCC and 82 controls using VP1 virus-like particles produced in insect cells.

Efficacy of infliximab for hidradenitis suppurativa: assessment of clinical and biological inflammatory markers.

Treatment of hidradenitis suppurativa (HS) is often unsatisfactory. The efficacy of infliximab for treatment of the disease has been suggested. The main objective of this study was to evaluate the efficacy and side-effects of infliximab in the treatment of moderate to severe HS, resistant to local and systemic treatments.

[Priapism: a severe paediatric complication of Fabry disease].

Fabry disease is an X-linked recessive lysosomal storage disorder caused by α-galactosidase A deficiency. Although the disease presents in childhood, diagnosis is often delayed to adulthood or missed, presumably due to the lack of specificity of the symptoms and to the absence of major complication during the paediatric years. We report a 9-year-old boy known to have a Fabry disease who presented an episode of priapism.

Changes in the nail unit in patients with secondary lymphoedema identified using clinical, dermoscopic and ultrasound examination.

Background: Secondary lymphoedema is characterized by lymphatic stasis that is often the result of a lymph node lesion. At advanced stages it may cause trophic changes in the skin. However, the presence of changes in the nail unit has not been reported to date.

Ultrastructural demonstration of a relationship between acquired cutis laxa and monoclonal gammopathy.

Acquired cutis laxa is an uncommon disorder sometimes associated with monoclonal gammopathy and multiple myeloma, although the mechanism of this link is unclear. We report here a case of a 34-year-old man with generalized acquired cutis laxa and monoclonal light chain disease with renal and neurological involvement. Electron microscopy examination of a skin sample revealed shortened and fragmented elastic fibres in the reticular dermis and normal collagen bundles.

High-resolution ultrasonography assists the differential diagnosis of blue naevi and cutaneous metastases of melanoma.

Background: Metastases of cutaneous melanoma may simulate benign blue naevi clinically.

Objectives: To investigate the value of ultrasonography in the differential diagnosis of lesions that look similar clinically, i.e.

Low-frequency ultrasound sonophoresis to increase the efficiency of topical steroids: a pilot randomized study of humans.

Topical steroids are efficient in vasoconstriction potential, which is linked to their anti-inflammatory activity. Low-frequency ultrasound (US) applied on the skin (sonophoresis) may enhance the transdermal transport of various steroids. We aimed to assess, in a simple, blinded, randomized controlled pilot study, the clinical efficiency of sonophoresis in increasing vasoconstriction by enhancing the transdermal penetration of topical steroids in human skin.

[Cutaneous ulcers and glycogen storage disease type 1b].

Background: Glycogen storage disease type 1b is a rare disorder caused by 6-glucose-phosphatase transport deficiency. It is characterised primarily by metabolic disorders combined with hypoglycaemia and hyperlactacidaemia and a predisposition to staphylococcal infections associated with polynuclear neutrophil abnormality. Herein, we report the case of a patient with glycogen storage disease type 1b who developed ulcers of the lower limbs and we discuss the possible significance of this association which, to our knowledge, has not yet been described in the medical literature.

Successful treatment of ulcerated haemangioma with propranolol.

Background: Ulceration is a frequent complication of proliferating haemangioma.

Methods: Four patients with ulcerated hemangioma aged 2, 4, 5 months and 5 weeks were treated with 2 mg/kg KG propranolol.

Results: Efficacy and safety of propranolol were excellent in all four cases.